Shank3 protein

Author: rmql

August undefined, 2024

WebbSHANK3 encodes a protein that is essential for proper functioning of the synapse, the junction between neurons. Relevance to autism: Both spontaneous and inherited … Webb9 jan. 2024 · Protein homeostasis (proteostasis) is crucial to the maintenance of neuronal integrity and function. As the contact sites between neurons, synapses rely heavily on precisely regulated protein-protein interactions to support synaptic transmission and plasticity processes. Autophagy is an effective degradative pathway that can digest …

Shank synaptic scaffold proteins: keys to understanding the ...

WebbSci-Hub Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nature Genetics, 39 (1), 25–27 10.1038/ng1933 sci hub to open science ↓ save Durand, C. M., Betancur, C., Boeckers, T. M., Bockmann, J., Chaste, P., Fauchereau, F., … Bourgeron, T. (2006). WebbHuR is an RNA-binding protein implicated in immune homeostasis and various cancers, including colorectal cancer. HuR binding to AU-rich elements within the 3' untranslated region of mRNAs... bayu satria

Shank3 modulates sleep and expression of circadian transcription ...

WebbNo crossreactivity against Shank2 or Shank3. Research Areas. Scaffolds. Conjugation. Unconjugated. Product Properties; Research Use Only. For reseaech use only, not for human or dignostic use. Target; Target. SHANK1. ... Thank you for your interest in NeuroMab™ Anti-Shank1/ SPANK-1/Synamon/SSTRIP scaffold protein, Clone N22/21. WebbIch bin Carolina Urrutia-Ruiz, eine erfahrene Forscherin, die Grundlagen- und angewandte Forschung betreibt. Ich bin ergebnisorientiert, wissbegierig, neugierig und lernbegierig. Daher möchte ich mit meiner Kreativität einen Beitrag leisten, indem ich innovative Lösungen zur Generierung von Wissen in klinischen Studien, Forschung und … Webbshank3, gtpase, synaptic scaffold protein, structural protein-signaling protein complex, structural protein/signaling protein: Biological source: Mus musculus (Mouse) More: Total number of polymer chains: 8: Total formula weight: 240414.66: Authors: david okeke utah

Autism-linked gene primes stress vulnerability in mice

Webb功能: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. WebbAnti-SHANK3 antibody produced in rabbit (Anti-Fragment ); Prestige Antibody powered by ... Anti-SH3 and multiple ankyrin repeat domains protein 3, Anti-Shank3. MDL number: … david okolica mdWebbUsing five autism-related mouse models, Shank3+/ΔC, Mecp2 (R308/Y), Cntnap2-/-, L7-Tsc1 (L7/Pcp2 (Cre)::Tsc1 (flox/+)), and patDp (15q11-13)/+, we report specific perturbations in delay eyeblink... david okit zala calme audio

"SH3 and multiple ankyrin repeat domains 3 (Shank3), also known as proline-rich synapse-associated protein 2 (ProSAP2), is a protein that in humans is encoded by the SHANK3 gene on chromosome 22. Additional isoforms have been described for this gene but they have not yet been experimentally verified. Visa mer This gene is a member of the Shank gene family. The gene encodes a protein that contains 5 interaction domains or motifs including the ankyrin repeats domain (ANK), a src 3 domain (SH3), a proline-rich domain, a Visa mer Mutations in this gene are associated with autism spectrum disorder. This gene is often missing in patients with 22q13.3 deletion syndrome (Phelan-McDermid syndrome), although … Visa mer A rat model of SHANK3 was developed using zinc finger nucleases targeting exon 6 of the ankyrin (ANK) repeat domain. The deletion (-68bp) resulted in reduction of the full length … Visa mer • GeneReviews/NCBI/NIH/UW entry on Phelan-McDermid or 22q13.3 deletion syndrome Visa mer SHANK3 has been shown to interact with ARHGEF7. Visa mer Mouse models of SHANK3 include N-terminal knock-outs and a PDZ domain knock-out all of which also show social interaction deficits … Visa mer • Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, … Visa mer " - Shank3 protein

Shank synaptic scaffold proteins: keys to understanding the ...

Shank3 modulates sleep and expression of circadian transcription ...

Shank3 protein

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