Ctr copper transporter family protein

Author: admo

August undefined, 2024

WebFigure 1. Bioinformatic analysis identifies C. thermophilum copper transporters. A, model showing a homotrimeric Ctr1/Ctr3 family protein complex with key Cys and Met residues involved in Cu + transport connected with a dashed red circle and key Gly residues involved in trimer stability via transmembrane helical packing highlighted with a red box. … WebMar 1, 2003 · Recently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in the plasma membrane as a homo-trimer.

Function and Regulation of the Plant COPT Family of High-Affinity ...

WebJan 5, 2024 · Enables copper ion transmembrane transporter activity. Involved in cellular copper ion homeostasis; copper ion transport; and regulation of heart rate. Located in plasma membrane. Is expressed in adult head. Orthologous to several human genes including SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of … WebCtr copper transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress … grams of gold to gbp

A differential subcellular localization of two copper ... - ScienceDirect

WebApr 21, 2011 · The copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in different species. The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Here we report the … WebOct 1, 2024 · The moss Physcomitrium (Physcomitrella) patens is a bryophyte that provides genetic information about the adaptation to the life on land by early Embryophytes and is a reference organism for comparative evolutionary studies in plants. Copper is an essential micronutrient for every living organism, its transport across the plasma membrane is … WebFeb 8, 2002 · This is the first report on the biochemical characterization of the human copper transporter hCtr1, which is important for understanding mechanisms for mammalian copper transport at the plasma membrane. The trace metal copper is an essential cofactor for a number of biological processes including mitochondrial oxidative … grams of fluorine to moles

Genome-wide identification and expression profiling of the copper …

Ctr1 and its role in body copper homeostasis - ScienceDirect

WebApr 1, 2013 · Copper is a vital mineral for many organisms, yet it is highly toxic as demonstrated by serious health concerns associated with its deficiency or excess accumulation. The SLC31 (CTR) family of... WebSep 25, 2024 · CTR1 belongs to a family of Copper Transporters that has at least six members (CTR1-6) among various organisms. Structural and functional divergence of the CTRs from lower organisms to mammals shed light on how the regulation of this protein family is modulated depending on the requirement and availability of copper. grams of fiber per day recommendationWebDec 13, 2024 · Gene Summary Copper transporter 1A ( Ctr1A) encodes a plasma membrane protein that functions as a copper transporter. It is required to drive neuropeptide maturation during normal growth and development. [Date last reviewed: 2024-03-07] ( FlyBase Gene Snapshot ) All Summaries Gene Snapshot Gene Group Key … chinatown in bangkok

"WebDec 1, 2015 · The COPT/Ctr family belongs to a highly conserved Ctr-like Cu transporter family. Most COPT/Ctr transporters contain 3 TMDs: TMD1, TMD2, and TMD3. The N terminus of most COPT/Ctr transporters includes methionine motifs involved in Cu binding that is important for facilitated import (Beaudoin et al., 2011). " - Ctr copper transporter family protein

Ctr copper transporter family protein

The copper transporter CTR1 provides an essential function

WebApr 11, 2024 · Arabidopsis copper transport protein COPT2 participates in the cross talk between iron deficiency responses and low-phosphate signaling. Plant Physiol., 162 (2013), ... Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol., 11 (2011), p. 69. View in Scopus Google Scholar

Did you know?

WebNov 1, 2006 · CTR1 belongs to the CTR (or SLC31A) family that includes CTR1/2 and P-type copper transporting ATPases (ATP7A and B). It is a 23-kDa channel-like transporter which has a unique pore for the transport of copper and three trans-membranes domains that oligomerize to form a functional trimer [85]. Webthe SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights …

WebThe reported Cu transporters are mainly from the COPT/Ctr protein family. Cu might be co-transported by COPT2, COPT3, and COPT4 with COPT6. ... Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol 11(1):69 WebMembers of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of the essential metal copper. Based on biochemical data, CTRs have three …

WebCopper uptake is regulated by CTR (copper transporter) family of proteins, which are highly conserved. High affinity copper uptake is facilitated by Ctr1 and Ctr3 in Saccharomyces cerevisiae and ... WebJul 21, 2014 · The family of proteins responsible for the transport of Cu in the reduced form is the COPT transport protein (copper transporter protein). These proteins are formed by five...

WebOct 30, 2024 · Among these, the main group is the COPT (COPper transporter)/Ctr (Copper transporter) proteins belonging to several protein families in diverse organisms (Puig and Thiele 2002). Another transporter type for Cu movement from cytosol into organelles in plants and humans is P-type adenosine triphosphate pump (Williams et al. …

WebMembers of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of … chinatown in dallas txWebJul 24, 2024 · Naturally, this localization of the receptors requires the transport of monovalent copper from the plasma membrane via the cytoplasm to the apoproteins in the ER-Golgi membranes. The identity of the copper carriers involved in this task and their cellular routes are not yet completely known. chinatown in canada torontoWebRecently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in … grams of gold to us dollarsWebNational Center for Biotechnology Information chinatown in brooklyn locationWebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ... chinatown in dominican republicWebin copper transport is currently lacking. According to computer algorithm analyses, Ctr family members contain three mem-brane-spanning domains, within which most of protein se-quence similarity lies. Biochemical and microscopy experi-ments in yeast and human cells have suggested that Ctr family members are integral membrane proteins that ... chinatown in dempster morton grove illinoisWebA different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes … grams of gold to oz