Chemistry and biology of nuciferine
WebAbstract. This study aimed to elucidate the mechanisms of nuciferine (a main aporphine alkaloid of lotus leaf extract), which can induce relaxation in contracted tracheal rings. Under Ca 2+ -free and 2 mM Ca 2+ conditions, we found that nuciferine had no effect on the resting muscle tone of tracheal rings. In contrast, nuciferine relaxed high K ... WebNuciferine ameliorated renal injury in mice with acute kidney injury, perhaps by inhibiting the ferroptosis. Nuciferine may represent a novel treatment that improves recovery from …
Chemistry and biology of nuciferine
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WebMar 17, 2024 · Lung cancer is a malignant tumor with the highest morbidity and mortality rates. Food therapy is a common adjuvant treatment for lung cancer due to its safety and painlessness. Developing new functional food and exploring novel drug targets is important for lung cancer adjuvant therapy. This study confirmed that the active ingredient …
WebHistology confirmed that the leaf extract and nuciferine prevented structural abnormality and inflammation in heart and liver tissues of treated groups. On in silico analysis, nuciferine showed stronger binding interaction with both β 1 and β 2 adrenergic receptors than isoproterenol. Hence, the leaf extract of N. nucifera and nuciferine ... WebMar 10, 2016 · Rationale The sacred lotus (Nelumbo nucifera) contains many phytochemicals and has a history of human use. To determine which compounds may be …
WebJan 1, 2024 · This overview comprehensively summarized the widespread knowledge regarding to the chemistry and biology of nuciferine including isolation techniques, total synthesis, structural modification and ... WebNuciferine (NF, PubChem CID: 10146) is an aromatic ring-containing alkaloid extracted from Nelumbo nucifera leaves and has a wide variety of pharmacological activities, such as lipid lowering (1 ...
WebSep 15, 2024 · Our previous study showed that nuciferine (NF) attenuated non-alcoholic fatty liver disease (NAFLD), which is attributed to a high-fat diet (HFD) through reinforcing intestinal barrier functions, regulating lipid metabolism, and improving inflammation. To clarify whether other mechanisms contribute to the anti-NAFLD efficacy of NF, the …
WebJan 15, 2024 · Nuciferine, a major bioactive compound isolated from the lotus leaf, possesses extensive pharmacological activities. Its effect on folic acid-induced acute kidney injury, however, remains unknown. Here, we aimed to clarify the pharmacological effects of nuciferine and its mechanisms of action in acute kidney injury. Experimental Approach burwood cinemaWebOct 15, 2015 · Nuciferine has shown remarkable biological activities and been considered as a promising drug. In this study, a sensitive and selective ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for determination of nuciferine in tissue and plasma. ... Chemistry, Biology; … hamro keyboard nepaliWebOct 22, 2024 · Antimicrobial peptides (AMPs) contain amphipathic structures and are derived from natural resources. AMPs have been found to be effective in treating the infections caused by antibiotic-resistant bacteria (ARB), and thus, are potential lead compounds against ARB. AMPs’ physicochemical properties, such as cationic nature, … hamroff glenn s mdWebSep 27, 2024 · Bilobalide, the only sesquiterpene compound from Ginkgo biloba leaf, exhibits various beneficial pharmaceutical activities, such as antioxidant, anti-inflammation, and protective effects for the central nervous system. Several bioactive components extracted from Ginkgo biloba extract reportedly have the potential to attenuate lipid … ham roast sizeWebJun 12, 2013 · Analysis of alkaloids in Lotus (Nelumbo nucifera Gaertn.) leaves by non-aqueous capillary electrophoresis using ultraviolet and mass spectrometric detection burwood cinema melbourneWebTussilagone (TUS), a natural sesquiterpene isolated from Tussilago farfara L, was explored in vitro and in vivo for its potential to treat non-alcoholic fatty liver disease, suggesting that TUS is a promising compound for the treatment of NAFLD. Non-alcoholic fatty liver disease (NAFLD) is a major health problem. However, no effective treatments are currently … burwood cinemas eventWebDing, Nuciferine promotes autophagy and reduces macrophage foaming by inhibiting PI3K/Akt/mTOR signaling pathway, Chin. J. Pathophysiol., № 36, с. 1230 Do, Analysis of … burwood cinema showtimes